Article
Contribution of the IL-17 Pathway to Psoriasis and Psoriatic Arthritis.
Current rheumatology reports - 1 Aug 2015
Durham L E, Kirkham B W, Taams L S
Abstract excerpt
Investigators have accrued compelling evidence that the IL-17 pathway is central to the pathogenesis of psoriasis and psoriatic arthritis. The evidence comprises genome-wide association studies (GWAS), data from experimental murine models and findings from in vitro studies on patients' cells or tissue biopsies. More recently, the success of drugs blocking the IL-17 pathway in treating both psoriasis (PsO) and...
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