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Article

Next-generation sequencing for hereditary breast and gynecologic cancer risk assessment.

Current opinion in obstetrics & gynecology - 1 Feb 2015

Kurian Allison W, Kingham Kerry E, Ford James M

Abstract excerpt

PURPOSE OF REVIEW: To summarize advances in next-generation sequencing and their application to breast and gynecologic cancer risk assessment. RECENT FINDINGS: Next-generation sequencing panels of 6-112 cancer-associated genes are increasingly used in patient care. Studies report a 4-16% prevalence of mutations other than BRCA1/2 among patients who meet evidence-based practice guidelines for BRCA1/2 testing, with...

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Genes, BRCA1
Genes, BRCA2
Genetic Counseling
Genital Neoplasms, Female
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Practice Guidelines as Topic

Risk Assessment

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PMID: 25502425
DOI: 10.1097/GCO.0000000000000141

Genes

BRCA1

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