Article
Expanded Gene Panel Use for Women With Breast Cancer: Identification and Intervention Beyond Breast Cancer Risk.
Annals of surgical oncology - 1 Oct 2017
O'Leary Erin, Iacoboni Daniela, Holle Jennifer, Michalski Scott T, Esplin Edward D, Yang Shan, Ouyang Karen
Abstract excerpt
BACKGROUND: Clinicians ordering multi-gene next-generation sequencing panels for hereditary breast cancer risk have a variety of test panel options. Many panels include lesser known breast cancer genes or genes associated with other cancers. The authors hypothesized that using broader gene panels increases the identification of clinically significant findings, some relevant and others incidental to the testing...
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