Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunogenicity and protective efficacy of Salmonella enterica serovar Pullorum pathogenicity island 2 mutant as a live attenuated vaccine candidate.

BMC veterinary research - 24 Jul 2015

Yin Junlei, Cheng Zhao, Xu Lijuan, Li Qiuchun, Geng Shizhong, Pan Zhiming, Jiao Xinan

Abstract excerpt

BACKGROUND: Salmonella enterica serovar Pullorum (S. Pullorum) causes Pullorum disease (PD), a severe systemic disease of poultry and results in considerable economic losses in developing countries. In order to develop a safe and immunogenic vaccine, the immunogenicity and protective efficacy of S06004ΔSPI2, a Salmonella pathogenicity island 2 (SPI2) deleted mutant of S. Pullorum was evaluated in 2-day old...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Vaccines
Share to Chickens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Cellular

Share to Immunity, Humoral

Share to Immunoglobulin G

Share to Salmonella enterica

Share to Salmonella Infections, Animal

Share to Vaccines, Attenuated

Source

Open in PubMed Open full text

Identifiers

PMID: 26205518
DOI: 10.1186/s12917-015-0497-3
PMCID: PMC4513372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunogenicity and protective efficacy of Salmonella enterica serovar Pullorum pathogenicity island 2 mutant as a live attenuated vaccine candidate.PMID 26205518Read ↗

Safety, Protective Immunity, and DIVA Capability of a Rough Mutant Salmonella Pullorum Vaccine Candidate in BroilersSemantic proximity Read ↗

The role of SPI-1 and SPI-2 type three secretion systems in persistent Salmonella enterica serovar Pullorum infections of chickenSemantic proximity Read ↗

Vaccination of chickens with Salmonella Pathogenicity Island (SPI) 1 and SPI2 defective mutants of Salmonella enterica serovar EnteritidisSemantic proximity Read ↗

Evaluation of the Safety and Protection Efficacy of spiC and nmpC or rfaL Deletion Mutants of Salmonella Enteritidis as Live Vaccine Candidates for Poultry Non-Typhoidal SalmonellosisSemantic proximity Read ↗

Oral immunization with an attenuated Salmonella Gallinarum encoding the H9N2 haemagglutinin and M2 ectodomain induces protective immune responses against H9N2 infection in chickens.Semantic proximity Read ↗

Effect of Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) deletion on intestinal colonization and systemic dissemination in chickensSemantic proximity Read ↗

Construction, characterization and evaluation of the protective efficacy of the Streptococcus suis double mutant strain ΔSsPep/ΔSsPspC as a live vaccine candidate in mice.Semantic proximity Read ↗

Vaccination of chickens with SPI1-lon and SPI1-lon-fliC mutant of Salmonella enterica Serovar Enteritidis.Semantic proximity Read ↗

Deletion of pagL and arnT genes that involved in LPS structure and charge modulation in Salmonella genome confer reduced endotoxicity and retained efficient protection against wild-type S. Gallinarium challenge in chickenSemantic proximity Read ↗

The Salmonella pathogenicity island 1 and Salmonella pathogenicity island 2 type III secretion systems play a major role in pathogenesis of systemic disease and gastrointestinal tract colonization of Salmonella enterica serovar Typhimurium in the chicken.Semantic proximity Read ↗

Evaluation of Salmonella enterica serovar Typhimurium TTSS-2 deficient fur mutant as safe live-attenuated vaccine candidate for immunocompromised mice.Semantic proximity Read ↗

Live Attenuated S. Typhimurium Vaccine with Improved Safety in Immuno-Compromised MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.