Article
Efavirenz and the CNS: what we already know and questions that need to be answered.
The Journal of antimicrobial chemotherapy - 1 Oct 2015
Apostolova Nadezda, Funes Haryes A, Blas-Garcia Ana, Galindo Maria J, Alvarez Angeles, Esplugues Juan V
Abstract excerpt
The NNRTI efavirenz has long been one of the most frequently employed antiretroviral drugs in the multidrug regimens used to treat HIV infection, in accordance with its well-demonstrated antiretroviral efficacy and favourable pharmacokinetics. However, growing concern about its adverse effects has sometimes led to efavirenz being replaced by other drugs in the initial treatment selection or to switching of...
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