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Article

Prediction and prevention of type 1 diabetes: update on success of prediction and struggles at prevention.

Pediatric diabetes - 1 Nov 2015

Michels Aaron, Zhang Li, Khadra Anmar, Kushner Jake A, Redondo Maria J, Pietropaolo Massimo

Abstract excerpt

Type 1 diabetes mellitus (T1DM) is the archetypal example of a T cell-mediated autoimmune disease characterized by selective destruction of pancreatic β cells. The pathogenic equation for T1DM presents a complex interrelation of genetic and environmental factors, most of which have yet to be identified. On the basis of observed familial aggregation of T1DM, it is certain that there is a decided heritable genetic...

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Identifiers

PMID: 26202050
DOI: 10.1111/pedi.12299
PMCID: PMC4592445

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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