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Article

Genome-wide uniparental disomy screen in human discarded morphologically abnormal embryos.

Scientific reports - 21 Jul 2015

Xu Jiawei, Zhang Meixiang, Niu Wenbin, Yao Guidong, Sun Bo, Bao Xiao, Wang Linlin, Du Linqing, Sun Yingpu

Abstract excerpt

Uniparental disomy (UPD) has been shown to be rare in human normal blastocysts, but its frequency in discarded morphologically abnormal embryos and its relevance to embryonic self-correction of aneuploid remains unknown. The aim of this study was to detect UPD in discarded morphologically abnormal embryos. Both discarded morphologically abnormal embryos, including zero-pronuclear zygotes (0PN), one-pronuclear...

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Source

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Identifiers

PMID: 26194013
DOI: 10.1038/srep12302
PMCID: PMC4508668

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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