Analysis of Molecular Markers by Anatomic Tumor Site in Stage III Colon Carcinomas from Adjuvant Chemotherapy Trial NCCTG N0147 (Alliance).

doi:10.1158/1078-0432.CCR-15-0527

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Analysis of Molecular Markers by Anatomic Tumor Site in Stage III Colon Carcinomas from Adjuvant Chemotherapy Trial NCCTG N0147 (Alliance).

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2015

Sinicrope Frank A, Mahoney Michelle R, Yoon Harry H, Smyrk Thomas C, Thibodeau Stephen N, Goldberg Richard M, Nelson Garth D, Sargent Daniel J, Alberts Steven R

Abstract excerpt

PURPOSE: To determine the frequency and prognostic association of molecular markers by anatomic tumor site in patients with stage III colon carcinomas. EXPERIMENTAL DESIGN: In a randomized trial of adjuvant FOLFOX ± cetuximab, BRAF(V600E) and KRAS (exon 2) mutations and DNA mismatch repair (MMR)...

Topics

Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols
Biomarkers, Tumor
Chemotherapy, Adjuvant
Clinical Trials, Phase III as Topic
Colonic Neoplasms
DNA Mismatch Repair
Female
Humans
Male
Middle Aged

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multicenter Studies as Topic

Mutation

Neoplasm Grading

Neoplasm Metastasis

Neoplasm Staging

Source

Open in PubMed Open full text

Identifiers

PMID: 26187617
DOI: 10.1158/1078-0432.CCR-15-0527
PMCID: PMC4668228

Genes

KRAS
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-26187617-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.