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Article

A cross-talk between Hepatitis B virus and host mRNAs confers viral adaptation to liver.

Scientific reports - 17 Jul 2015

Hu Jun, Xu Yaxing, Li Changfei, Hao Junli, Peng Shanxin, Chu Xiaoyu, Zhang Dake, Xu Dongping, Meng Songdong

Abstract excerpt

Hepatitis B virus (HBV) chronically infects approximately 350 million people worldwide. The replication of HBV which genome is only 3.2 kb long relies heavily on host factors. Previous studies demonstrated that a highly expressed liver-specific microRNA (miRNA) miR-122 suppresses HBV expression and replication in multiple ways. In this study, we found that the miR-122 response elements in viral genome facilitate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26184825
DOI: 10.1038/srep10572
PMCID: PMC4505342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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