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Article

Autonomous and non-autonomous roles of DNase II during cell death in C. elegans embryos.

Bioscience reports - 27 Apr 2015

Yu Hsiang, Lai Huey-Jen, Lin Tai-Wei, Lo Szecheng J

Abstract excerpt

Generation of DNA fragments is a hallmark of cell apoptosis and is executed within the dying cells (autonomous) or in the engulfing cells (non-autonomous). The TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labelling) method is used as an in situ assay of apoptosis by labelling DNA fragments generated by caspase-associated DNase (CAD), but not those by the downstream DNase II. In the present study, we...

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Identifiers

PMID: 26182365
DOI: 10.1042/BSR20150055
PMCID: PMC4613723

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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