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Article

Variants of the CLOCK gene affect the risk of idiopathic male infertility in the Han-Chinese population.

Chronobiology international - 1 Jan 2015

Shen Ouxi, Ding Xinliang, Nie Jihua, Xia Yankai, Wang Xinru, Tong Jian, Zhang Jie

Abstract excerpt

Recent experimental animal studies suggested that the circadian locomotor output cycles kaput protein gene (CLOCK) has been reported to play a critical role in sperm function and male fertility. The aim of this study was to determine whether variants of the CLOCK gene are involved in idiopathic male infertility. The study included 478 idiopathic infertile men and 194 fertile controls who completed physical...

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Source

Identifiers

PMID: 26181468
DOI: 10.3109/07420528.2015.1056305

Genes

CLOCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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