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Article

Association of CLOCK gene variants with semen quality in idiopathic infertile Han-Chinese males.

Reproductive biomedicine online - 1 Nov 2012

Zhang Jie, Ding Xinliang, Li Yingchun, Xia Yankai, Nie Jihua, Yi Cao, Wang Xinru, Tong Jian

Abstract excerpt

Recent experimental animal studies suggested that the circadian locomotor output cycles kaput protein gene (CLOCK) may play an important role in male reproduction. So far, such data for humans are not available. This study used single-nucleotide polymorphisms (SNP) to examine the association between CLOCK and semen quality in a human population with idiopathic infertility. Three-variant genotyping of CLOCK and...

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Source

Identifiers

PMID: 22999556
DOI: 10.1016/j.rbmo.2012.07.018

Genes

CLOCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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