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Article

Association of Somatic Mutations of ADAMTS Genes With Chemotherapy Sensitivity and Survival in High-Grade Serous Ovarian Carcinoma.

JAMA oncology - 1 Jul 2015

Liu Yuexin, Yasukawa Maya, Chen Kexin, Hu Limei, Broaddus Russell R, Ding Li, Mardis Elaine R, Spellman Paul, Levine Douglas A, Mills Gordon B, Shmulevich Ilya, Sood Anil K, Zhang Wei

Abstract excerpt

IMPORTANCE: Chemotherapy response in the majority of patients with ovarian cancer remains unpredictable. OBJECTIVE: To identify novel molecular markers for predicting chemotherapy response in patients with ovarian cancer. DESIGN, SETTING, AND PARTICIPANTS: Observational study of genomics and clinical data of high-grade serous ovarian cancer cases with genomic and clinical data made public between 2009 and 2014...

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Identifiers

PMID: 26181259
DOI: 10.1001/jamaoncol.2015.1432
PMCID: PMC4608536

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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