Article
Resistance to Innate Immunity Contributes to Colonization of the Insect Gut by Yersinia pestis.
PloS one - 1 Jan 2015
Earl Shaun C, Rogers Miles T, Keen Jennifer, Bland David M, Houppert Andrew S, Miller Caitlynn, Temple Ian, Anderson Deborah M, Marketon Melanie M
Abstract excerpt
Yersinia pestis, the causative agent of bubonic and pneumonic plague, is typically a zoonotic vector-borne disease of wild rodents. Bacterial biofilm formation in the proventriculus of the flea contributes to chronic infection of fleas and facilitates efficient disease transmission. However prior to biofilm formation, ingested bacteria must survive within the flea midgut, and yet little is known about...
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