Article
Yersinia pestis kills Caenorhabditis elegans by a biofilm-independent process that involves novel virulence factors.
EMBO reports - 1 Oct 2005
Styer Katie L, Hopkins Gregory W, Bartra Sara Schesser, Plano Gregory V, Frothingham Richard, Aballay Alejandro
Abstract excerpt
It is known that Yersinia pestis kills Caenorhabditis elegans by a biofilm-dependent mechanism that is similar to the mechanism used by the pathogen to block food intake in the flea vector. Using Y. pestis KIM 5, which lacks the genes that are required for biofilm formation, we show that Y. pestis can kill C. elegans by a biofilm-independent mechanism that correlates with the accumulation of the pathogen in the...
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