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Article

A Peripheral Blood Gene Expression Signature to Diagnose Subclinical Acute Rejection

5 Jul 2019

Abstract excerpt

Significance Statement Biomarkers for noninvasive diagnosis of subclinical acute rejection are needed to enable risk-stratification and tailoring of immunosuppression for kidney transplant recipients. Using RNA sequencing analyses of whole blood collected from a cohort of transplant recipients at the time of surveillance biopsy, the authors identified a transcriptional signature on the basis of a set of 17 genes...

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Share to Organ Transplantation Techniques and Outcomes
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Identifiers

PMID: 31278196
DOI: 10.1681/asn.2018111098

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