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Harnessing Pandemonium: The Clinical Implications of Tumor Heterogeneity in Ovarian Cancer

30 Jun 2015

Abstract excerpt

Heterogeneity has emerged as a key feature of ovarian cancer between different ovarian cancer subtypes; within single ovarian cancer subtypes; and within individual patient tumors. At the genomic level, with the advent of ultra-deep sequencing technologies alongside RNA-Seq, epigenomics, and proteomics, the complexity surrounding heterogeneity has deepened. Here, we summarize the emerging understanding of...

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PMID: 26175968
DOI: 10.3389/fonc.2015.00149

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