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Article

Transcription factor R ex in regulation of pathophysiology in oral pathogens

14 Jul 2015

Abstract excerpt

The NAD(+) and NADH-sensing transcriptional regulator Rex is widely conserved across gram-positive bacteria. Rex monitors cellular redox poise and controls the expression of genes/operons involved in diverse pathways including alternative fermentation, oxidative stress responses, and biofilm formation. The oral cavity undergoes frequent and drastic fluctuations in nutrient availability, pH, temperature, oxygen...

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PMID: 26172563
DOI: 10.1111/omi.12114

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