Article
Transcriptional repressor Rex is involved in regulation of oxidative stress response and biofilm formation by Streptococcus mutans.
FEMS microbiology letters - 1 Jul 2011
Bitoun Jacob P, Nguyen Anne H, Fan Yuwei, Burne Robert A, Wen Zezhang T
Abstract excerpt
The transcriptional repressor Rex has been implicated in the regulation of energy metabolism and fermentative growth in response to redox potential. Streptococcus mutans, the primary causative agent of human dental caries, possesses a gene that encodes a protein with high similarity to members of the Rex family of proteins. In this study, we showed that Rex-deficiency compromised the ability of S. mutans to cope...
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