Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between the Haptoglobin 2 Phenotype and Diabetes Mellitus on Systolic Pulmonary Arterial Pressure and Nitric Oxide Bioavailability in Hemodialysis Patients.

Journal of diabetes research - 1 Jan 2015

Dahan Inbal, Farber Evgeny, Thauho Nadia, Nakhoul Nakhoul, Francis Adi, Awawde Mohamad, Levy Andrew P, Kim-Shapiro Daniel B, Basu Swati, Nakhoul Farid

Abstract excerpt

Elevated systolic pulmonary artery pressure (s-PAP, ≥35 mmHg) serves as an independent predictor of mortality in hemodialysis (HD) and diabetic (DM) patients. A polymorphism in the antioxidant Haptoglobin (Hp) gene has been shown to regulate the bioavailability of nitric oxide (NO), a major mediator of pulmonary vascular tone. We therefore set out to test the hypothesis that the Hp polymorphism may be a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arterial Pressure
Share to Diabetes Complications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Echocardiography

Share to Haptoglobins

Share to Hypertension, Pulmonary

Share to Nitrites

Share to Pulmonary Artery

Share to Renal Dialysis

Source

Open in PubMed Open full text

Identifiers

PMID: 26171400
DOI: 10.1155/2015/613860
PMCID: PMC4481085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between the Haptoglobin 2 Phenotype and Diabetes Mellitus on Systolic Pulmonary Arterial Pressure and Nitric Oxide Bioavailability in Hemodialysis Patients.PMID 26171400Read ↗

Is it time to screen for the haptoglobin genotype to assess the cardiovascular risk profile and vitamin E therapy responsiveness in patients with diabetes?Semantic proximity Read ↗

In vivo and in vitro studies establishing haptoglobin as a major susceptibility gene for diabetic vascular disease.Semantic proximity Read ↗

Haptoglobin phenotype as a predictive factor of mortality in diabetic haemodialysis patients.Semantic proximity Read ↗

Application of pharmacogenomics in the prevention of diabetic cardiovascular disease: mechanistic basis and clinical evidence for utilization of the haptoglobin genotype in determining benefit from antioxidant therapy.Semantic proximity Read ↗

Interaction Between the Haptoglobin Genotype and Vitamin E on Cardiovascular Disease in Diabetes.Semantic proximity Read ↗

Haptoglobin genotype and its role in determining heme-iron mediated vascular disease.Semantic proximity Read ↗

Anti-oxidative treatment with vitamin E improves peripheral vascular function in patients with diabetes mellitus and Haptoglobin 2-2 genotype: A double-blinded cross-over study.Semantic proximity Read ↗

Haptoglobin genotype is a regulator of reverse cholesterol transport in diabetes in vitro and in vivo.Semantic proximity Read ↗

The Role of Haptoglobin Polymorphism in Cardiovascular Disease in the Setting of Diabetes.Semantic proximity Read ↗

Divergent effects of alpha-tocopherol and vitamin C on the generation of dysfunctional HDL associated with diabetes and the Hp 2-2 genotype.Semantic proximity Read ↗

Relation of haptoglobin phenotype to early vascular changes in patients with diabetes mellitus.Semantic proximity Read ↗

Haptoglobin polymorphism and peripheral arterial occlusive disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.