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SAPCD2 promotes neuroblastoma progression by altering the subcellular distribution of E2F7

23 Feb 2022

Abstract excerpt

Recent studies uncovered the emerging roles of SAPCD2 (suppressor anaphase-promoting complex domain containing 2) in several types of human cancer. However, the functions and underlying mechanisms of SAPCD2 in the progression of neuroblastoma (NB) remain elusive. Herein, through integrative analysis of public datasets and regulatory network of GSK-J4, a small-molecule drug with anti-NB activity, we identified...

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PMID: 35197448
DOI: 10.1038/s41419-022-04624-z

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