Article
Partitioning of genomic variance reveals biological pathways associated with udder health and milk production traits in dairy cattle.
Genetics, selection, evolution : GSE - 14 Jul 2015
Edwards Stefan M, Thomsen Bo, Madsen Per, Sørensen Peter
Abstract excerpt
BACKGROUND: We have used a linear mixed model (LMM) approach to examine the joint contribution of genetic markers associated with a biological pathway. However, with these markers being scattered throughout the genome, we are faced with the challenge of modelling the contribution from several, sometimes even all, chromosomes at once. Due to linkage disequilibrium (LD), all markers may be assumed to account for...
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