Article
Virulence, Host-Selective Toxin Production, and Development of Three Cochliobolus Phytopathogens Lacking the Sfp-Type 4'-Phosphopantetheinyl Transferase Ppt1.
Molecular plant-microbe interactions : MPMI - 1 Oct 2015
Zainudin Nur Ain Izzati Mohd, Condon Bradford, De Bruyne Lieselotte, Van Poucke Christof, Bi Qing, Li Wei, Höfte Monica, Turgeon B Gillian
Abstract excerpt
The Sfp-type 4'-phosphopantetheinyl transferase Ppt1 is required for activation of nonribosomal peptide synthetases, including α-aminoadipate reductase (AAR) for lysine biosynthesis and polyketide synthases, enzymes that biosynthesize peptide and polyketide secondary metabolites, respectively. Deletion of the PPT1 gene, from the maize pathogen Cochliobolus heterostrophus and the rice pathogen Cochliobolus...
Topics
- Ascomycota
- Bacterial Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Iron
- L-Aminoadipate-Semialdehyde Dehydrogenase
- Mutation
- Mycotoxins
- Oryza
- Oxidative Stress
- Peptide Synthases
- Phenotype