Functional Analysis of All Nonribosomal Peptide Synthetases in <i>Cochliobolus heterostrophus</i> Reveals a Factor, NPS6, Involved in Virulence and Resistance to Oxidative Stress

Abstract excerpt

Nonribosomal peptides, made by nonribosomal peptide synthetases, have diverse biological activities, including roles as fungal virulence effectors. Inspection of the genome of Cochliobolus heterostrophus, a fungal pathogen of maize and a member of a genus noted for secondary metabolite production, revealed eight multimodular nonribosomal peptide synthase (NPS) genes and three monomodular NPS-like genes, one of...

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