Toxin-deficient mutants from a toxin-sensitive transformant of Cochliobolus heterostrophus.

doi:10.1093/genetics/137.3.751

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Article

Toxin-deficient mutants from a toxin-sensitive transformant of Cochliobolus heterostrophus.

Genetics - 1 Jul 1994

Yang G, Turgeon B G, Yoder O C

Abstract excerpt

Tox1 is the only genetic element identified which controls production of T-toxin, a linear polyketide involved in the virulence of Cochliobolus heterostrophus to its host plant, corn. Previous attempts to induce toxin-deficient (Tox-) mutants, using conventional mutagenesis and screening procedures, have been unsuccessful. As a strategy to enrich for Tox- mutants, we constructed a Tox1+ strain that carried the...

Topics

Ascomycota
Aspergillus nidulans
Cloning, Molecular
Crosses, Genetic
DNA, Mitochondrial
Ethyl Methanesulfonate
Fertility
Gene Expression
Gene Transfer Techniques
Genes, Fungal
Genes, Plant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mitochondria

Mitochondrial Proteins

Mutation

Mycotoxins

Plant Diseases

Plant Proteins

Plasmids

Source

Open in PubMed Open full text

Identifiers

PMID: 8088521
DOI: 10.1093/genetics/137.3.751
PMCID: PMC1206035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8088521-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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