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Tumour Necrosis Factor-α Gene Polymorphism Is Associated with Metastasis in Patients with Triple Negative Breast Cancer.

Scientific reports - 13 Jul 2015

Li Hui-Hui, Zhu Hui, Liu Li-Sheng, Huang Yong, Guo Jun, Li Jie, Sun Xin-Ping, Chang Chun-Xiao, Wang Zhe-Hai, Zhai Kan

Abstract excerpt

Tumour necrosis factor-α (TNF-α) is critical in the regulation of inflammation and tumour progression. TNF-α-308G > A is associated with constitutively elevated TNF-α expression. The purpose of this study was to assess the association between TNF-α-308G > A and breast cancer (BC) risk by subtype and the connection between genotypes and clinical features of BC. A total of 768 patients and 565 controls were...

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Identifiers

PMID: 26165253
DOI: 10.1038/srep10244
PMCID: PMC4499887

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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