Article
Association of TNF-α, TNFRSF1A and TNFRSF1B gene polymorphisms with the risk of sporadic breast cancer in northeast Chinese Han women.
PloS one - 1 Jan 2014
Xu Fengyan, Zhou Guiqin, Han Shaoli, Yuan Weiguang, Chen Shuang, Fu Zhenkun, Li Dalin, Zhang Hua, Li Dianjun, Pang Da
Abstract excerpt
BACKGROUND: The interaction of tumor necrosis factor-α (TNF-α) with its receptors: TNFRSF1A and TNFRSF1B is critical for the promotion of tumor growth, invasion and metastasis. To better understand the roles of single nucleotide polymorphisms (SNPs) in the TNF-α, TNFRSF1A and TNFRSF1B genes in the development of breast cancer, we explored the associations between SNPs in these three genes and breast cancer...
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