Article
[Analyses of Binding Profiles of the GII. 12 Norovirus with Human Histo-blood Group Antigens].
Bing du xue bao = Chinese journal of virology - 1 Mar 2015
Jin Miao, Chen Kena, Song Jingdong, Li Huiying, Zhang Qing, Kong Xiangyu, Liu Na, Duan Zhaojun
Abstract excerpt
Interactions between noroviruses (NoVs) and the receptors of histo-blood group antigens (HB-GAs) affect the infectivity and host susceptibility of NoVs. We elucidated the binding profile of a GII. 12 NoV to HBGAs. First, we synthesized the P domain sequence of the GII. 12 NoV strain Pune (GenBank accession number EU921353). Protein of the P domain was expressed in a prokaryotic system. Formation of the P particle...
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