Article
Norovirus-host interaction: multi-selections by human histo-blood group antigens.
Trends in microbiology - 1 Aug 2011
Tan Ming, Jiang Xi
Abstract excerpt
The discovery of human histo-blood group antigens (HBGAs) as receptors or ligands of noroviruses (NoVs) raises a question about the potential role of host factors in the evolution and diversity of NoVs. Recent structural analysis of selected strains in the two major genogroups of human NoVs (GI and GII) demonstrated highly conserved HBGA binding interfaces within the two groups but not between them, indicating...
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