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Article

Gene Loss Dominates As a Source of Genetic Variation within Clonal Pathogenic Bacterial Species.

Genome biology and evolution - 10 Jul 2015

Bolotin Evgeni, Hershberg Ruth

Abstract excerpt

Some of the most dangerous pathogens such as Mycobacterium tuberculosis and Yersinia pestis evolve clonally. This means that little or no recombination occurs between strains belonging to these species. Paradoxically, although different members of these species show extreme sequence similarity of orthologous genes, some show considerable intraspecies phenotypic variation, the source of which remains elusive. To...

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Identifiers

PMID: 26163675
DOI: 10.1093/gbe/evv135
PMCID: PMC4558853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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