Article
Phylogenetic understanding of clonal populations in an era of whole genome sequencing.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2009
Pearson Talima, Okinaka Richard T, Foster Jeffrey T, Keim Paul
Abstract excerpt
Phylogenetic hypotheses using whole genome sequences have the potential for unprecedented accuracy, yet a failure to understand issues associated with discovery bias, character sampling, and strain sampling can lead to highly erroneous conclusions. For microbial pathogens, phylogenies derived from whole genome sequences are becoming more common, as large numbers of characters distributed across entire genomes can...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.