Article
Mammographic density and breast cancer in women from high risk families.
Breast cancer research : BCR - 11 Jul 2015
Ramón Y Cajal Teresa, Chirivella Isabel, Miranda Josefa, Teule Alexandre, Izquierdo Ángel, Balmaña Judith, Sánchez-Heras Ana Beatriz, Llort Gemma, Fisas David, Lope Virginia, Hernández-Agudo Elena, Juan-Fita María José, Tena Isabel, Robles Luis, Guillén-Ponce Carmen, Pérez-Segura Pedro, Luque-Molina Mari Sol, Hernando-Polo Susana, Salinas Mónica, Brunet Joan, Salas-Trejo María Dolores, Barnadas Agustí, Pollán Marina
Abstract excerpt
INTRODUCTION: Mammographic density (MD) is one of the strongest determinants of sporadic breast cancer (BC). In this study, we compared MD in BRCA1/2 mutation carriers and non-carriers from BRCA1/2 mutation-positive families and investigated the association between MD and BC among BRCA1/2 mutation carriers per type of mutation and tumor subtype. METHODS: The study was carried out in 1039 female members of BRCA1...
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