Article
Mammographic density does not differ between unaffected BRCA1/2 mutation carriers and women at low-to-average risk of breast cancer.
Breast cancer research and treatment - 1 Aug 2010
Gierach Gretchen L, Loud Jennifer T, Chow Catherine K, Prindiville Sheila A, Eng-Wong Jennifer, Soballe Peter W, Giambartolomei Claudia, Mai Phuong L, Galbo Claudia E, Nichols Kathryn, Calzone Kathleen A, Vachon Celine, Gail Mitchell H, Greene Mark H
Abstract excerpt
Elevated mammographic density (MD) is one of the strongest risk factors for sporadic breast cancer. Epidemiologic evidence suggests that MD is, in part, genetically determined; however, the relationship between MD and BRCA1/2 mutation status is equivocal. We compared MD in unaffected BRCA1/2 mutation carriers enrolled in the U.S. National Cancer Institute's Clinical Genetics Branch's Breast Imaging Study (n =...
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