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Article

Changes in peripheral blood immune cell composition in osteoarthritis

8 Jul 2015

Abstract excerpt

OBJECTIVES: Immune age-related abnormalities may synergise with osteoarthritis (OA) pathology. We explored whether abnormalities in the blood immune cell composition are present in OA, beyond defects typically associated with ageing. DESIGN: Blood was collected from 121 healthy controls (HC) and 114 OA patients. Synovial biopsies were obtained from another 52 OA patients. Flow cytometry was used to establish the...

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PMID: 26162804
DOI: 10.1016/j.joca.2015.06.018

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