Article
The Role of Amino Acid Permeases and Tryptophan Biosynthesis in Cryptococcus neoformans Survival.
PloS one - 1 Jan 2015
Fernandes João Daniel Santos, Martho Kevin, Tofik Veridiana, Vallim Marcelo A, Pascon Renata C
Abstract excerpt
Metabolic diversity is an important factor during microbial adaptation to different environments. Among metabolic processes, amino acid biosynthesis has been demonstrated to be relevant for survival for many microbial pathogens, whereas the association between pathogenesis and amino acid uptake and recycling are less well-established. Cryptococcus neoformans is an opportunistic fungal pathogen with many habitats....
Topics
- Amino Acid Transport Systems
- Biosynthetic Pathways
- Cryptococcus neoformans
- Fungal Proteins
- Gene Deletion
- Gene Expression Profiling
- Gene Expression Regulation, Fungal
- Genes, Essential
- Genes, Fungal
- Microbial Sensitivity Tests
- Microbial Viability
- Mutation
- Nitrogen