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Article

Global nutritional profiling for mutant and chemical mode-of-action analysis in filamentous fungi.

Functional & integrative genomics - 1 Dec 2003

Tanzer Matthew M, Arst Herbert N, Skalchunes Amy R, Coffin Marie, Darveaux Blaise A, Heiniger Ryan W, Shuster Jeffrey R

Abstract excerpt

We describe a method for gene function discovery and chemical mode-of-action analysis via nutrient utilization using a high throughput Nutritional Profiling platform suitable for filamentous microorganisms. We have optimized the growth conditions for each fungal species to produce reproducible optical density growth measurements in microtiter plates. We validated the Nutritional Profiling platform using a...

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PMID: 12898394
DOI: 10.1007/s10142-003-0089-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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