Article
Racial Differences in BRAF/KRAS Mutation Rates and Survival in Stage III Colon Cancer Patients.
Journal of the National Cancer Institute - 1 Oct 2015
Yoon Harry H, Shi Qian, Alberts Steven R, Goldberg Richard M, Thibodeau Stephen N, Sargent Daniel J, Sinicrope Frank A
Abstract excerpt
BACKGROUND: It is unknown if, after controlling for clinicopathologic variables and treatment, racial disparities in colon cancer outcomes persist. Molecular marker analysis in North American patients comparing Asians with other races has not been reported. METHODS: BRAF (V600E) and KRAS mutation...
Topics
- Adult
- Aged
- Asian People
- Black People
- Colonic Neoplasms
- Confounding Factors, Epidemiologic
- DNA Mismatch Repair
- Disease-Free Survival
- Female
- Humans
- Male
- Middle Aged
- Mutation
- Neoplasm Grading
- Neoplasm Staging