Article
Variation in KRAS/NRAS/BRAF-Mutation Status by Age, Sex, and Race/Ethnicity Among a Large Cohort of Patients with Metastatic Colorectal Cancer (mCRC).
Journal of gastrointestinal cancer - 1 Mar 2024
Booker Benjamin D, Markt Sarah C, Schumacher Fredrick R, Rose Johnie, Cooper Greg, Selfridge J Eva, Koroukian Siran M
Abstract excerpt
BACKGROUND: Racial/ethnic disparities in metastatic colorectal cancer (mCRC) survival are well documented as is the impact that tumor mutation of KRAS and BRAF has on prognosis. It has been suggested that frequency differences of KRAS- and BRAF-mutated tumors may partially explain this disparity. Demographic differences in mutation frequency are not well established nor whether mutation and microsatellite...
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