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Article

Somatic gene mutations in African Americans may predict worse outcomes in colorectal cancer.

Cancer biomarkers : section A of Disease markers - 1 Jan 2013

Kang Melissa, Shen Xiang J, Kim Sangmi, Araujo-Perez Felix, Galanko Joseph A, Martin Chris F, Sandler Robert S, Keku Temitope O

Abstract excerpt

BACKGROUND AND OBJECTIVE: African Americans have worse outcomes in colorectal cancer (CRC) than Caucasians. We sought to determine if KRAS, BRAF and PIK3CA mutations might contribute to the racial differences in CRC outcome. METHODS: DNA was extracted from tissue microarrays made from CRC samples...

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Source

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Identifiers

PMID: 24440976
DOI: 10.3233/CBM-130366
PMCID: PMC4589188

Genes

BRAF
KRAS
PIK3CA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24440976-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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