Article
Effect of angiotensin-converting enzyme gene insertion/deletion polymorphism on steroid resistance in Egyptian children with idiopathic nephrotic syndrome.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Jun 2010
Saber-Ayad Maha, Sabry Samar, Abdel-Latif Inas, Nabil Hanaa, El-Azm Soheir Abo, Abdel-Shafy Sanaa
Abstract excerpt
INTRODUCTION: The presence of the deletion (D) allele in the angiotensin-converting enzyme (ACE) gene has been reported as a probable genetic risk factor for idiopathic nephrotic syndrome (INS), but its role in determining resistance to steroid therapy remains to be evaluated. METHODS: Fifty-one patients were enrolled in the study and received oral steroids. The pattern of response to steroid therapy was...
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