Article
HPV6 variants from malignant tumors with sequence alterations in the regulatory region do not reveal differences in the activities of the oncogene promoters but do contain amino acid exchanges in the E6 and E7 proteins.
Virology - 1 Sept 1996
Grassmann K, Wilczynski S P, Cook N, Rapp B, Iftner T
Abstract excerpt
Human papillomavirus type 6 (HPV6) causes benign epithelial proliferations of the anogenital and aerodigestive tract, which usually tend to regress spontaneously. The low incidence of HPV6 in carcinomas and the rare progression of the benign tumors has led to the classification of HPV6 as "low-ri...
Topics
- Base Sequence
- DNA, Viral
- Female
- Genetic Variation
- Humans
- Male
- Molecular Sequence Data
- Oncogene Proteins, Viral
- Oncogenes
- Papillomaviridae
- Papillomavirus Infections
- Promoter Regions, Genetic
- Regulatory Sequences, Nucleic Acid
- Sequence Homology, Nucleic Acid