Article
Glycan-Dependent Neutralizing Antibodies Are Frequently Elicited in Individuals Chronically Infected with HIV-1 Clade B or C.
AIDS research and human retroviruses - 1 Nov 2015
Cohen Yehuda Z, Lavine Christy L, Miller Caroline A, Garrity Jetta, Carey Brittany R, Seaman Michael S
Abstract excerpt
A number of potent broadly neutralizing antibodies against HIV-1 have recently been identified that target epitopes on the viral envelope that contain N-linked glycans. It remains unknown how frequently glycan-dependent neutralizing antibodies generally arise during the course of natural infection or whether particular glycosylation sites are preferentially targeted. We tested sera with a broad range of...
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