Article
Warfarin pharmacogenomics: current best evidence.
Journal of thrombosis and haemostasis : JTH - 1 Jun 2015
Kimmel S E
Abstract excerpt
The utility of using genetic information to guide warfarin dosing has remained unclear based on prior observational studies and small clinical trials. Two larger trials of warfarin and one of the acenocoumarol and phenprocoumon have recently been published. The COAG trial addressed the incremental benefit of adding genetic information to clinical information and demonstrated no benefit from the...
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