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Article

The genetics of human running: ACTN3 polymorphism as an evolutionary tool improving the energy economy during locomotion.

Annals of human biology - 1 May 2016

Pasqua Leonardo A, Bueno Salomão, Matsuda Monique, Marquezini Mônica V, Lima-Silva Adriano E, Saldiva Paulo H N, Bertuzzi Rômulo

Abstract excerpt

BACKGROUND: Covering long distances was an important trait to human evolution and continues to be highlighted for health and athletic status. This ability is benefitted by a low cost of locomotion (CoL), meaning that the individuals who are able to expend less energy would be able to cover longer distances. The CoL has been shown to be influenced by distinct and even 'opposite' factors, such as physiological and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26148057
DOI: 10.3109/03014460.2015.1050065

Genes

ACTN3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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