Article
Polymorphism of Interleukin-10 (IL-10, -1082 G/A) and Interleukin-28B (IL-28B, C/T) In Pediatric Acute Lymphoblastic Leukemia (ALL).
Pakistan journal of pharmaceutical sciences - 1 Sept 2019
Ghufran Hafiz, Riaz Sehar, Mahmood Nasir, Yaqoob Muhammad, Shahid Saman, Bhinder Munir Ahmad, Anwar Saadia, Faizan Mahwish
Abstract excerpt
We conducted genotypic analyses of interleukin-10 (IL-10) (-1082 G/A; GG, GA, AA) and interleukin-28B (CC, CT, TT) genes polymorphisms in acute lymphoblastic leukemia (ALL) pediatric patients in descriptive study to evaluate the prevalence of these mutations. In amplification refractory mutation system-PCR (ARMS-PCR), one reaction was carried out for each patient's DNA sample. For IL-28B gene, two forward and two...
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