Neuroblastoma: the impact of biology and cooperation leading to personalized treatments.

doi:10.3109/10408363.2012.683483

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Article

Neuroblastoma: the impact of biology and cooperation leading to personalized treatments.

Critical reviews in clinical laboratory sciences - 1 Jan 2000

Owens Cormac, Irwin Meredith

Abstract excerpt

Neuroblastoma is the most common extra-cranial solid tumor in children. It is a heterogeneous disease, consisting of neural crest-derived tumors with remarkably different clinical behaviors. It can present in a wide variety of ways, including lesions which have the potential to spontaneously regress, or as an extremely aggressive form of metastatic cancer which is resistant to all forms of modern therapy. They...

Topics

Biomarkers
Child, Preschool
Chromosome Aberrations
Diagnostic Imaging
Genetic Predisposition to Disease
Humans
Infant
Loss of Heterozygosity
N-Myc Proto-Oncogene Protein
Neoplasm Staging
Neuroblastoma
Nuclear Proteins
Oncogene Proteins
Receptor, trkA
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 22646747
DOI: 10.3109/10408363.2012.683483

Genes

MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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