Article
Monotherapy versus combination therapy for the treatment of chronic hepatitis B.
Expert opinion on investigational drugs - 1 Nov 2009
Carey Ivana, Harrison Phillip M
Abstract excerpt
BACKGROUND: Nucleos(t)ide analogues, active against hepatitis B polymerase, suppress viral replication and improve clinical outcome. However, the emergence of drug-resistant mutants can result in treatment failure. OBJECTIVES: We describe how the choice of first-line therapy is critical to long-term treatment success. METHODS: A review of current drug therapies is provided. RESULTS/CONCLUSIONS: Monotherapy with...
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