Article
Potential of promotion of alleles by genome editing to improve quantitative traits in livestock breeding programs.
Genetics, selection, evolution : GSE - 2 Jul 2015
Jenko Janez, Gorjanc Gregor, Cleveland Matthew A, Varshney Rajeev K, Whitelaw C Bruce A, Woolliams John A, Hickey John M
Abstract excerpt
BACKGROUND: Genome editing (GE) is a method that enables specific nucleotides in the genome of an individual to be changed. To date, use of GE in livestock has focussed on simple traits that are controlled by a few quantitative trait nucleotides (QTN) with large effects. The aim of this study was to evaluate the potential of GE to improve quantitative traits that are controlled by many QTN, referred to here as...
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