Article
CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis.
Genetics and molecular research : GMR - 18 May 2015
Wang X, He Y
Abstract excerpt
Cytochrome P4502E1 (CYP2E1) is a key enzyme in the metabolic activation of many carcinogens, but the roles of CYP2E1 polymorphisms in cervical neoplasia (CN) are inconclusive. Published case-control cohort studies from the Pubmed, Embase, and China National Knowledge Infrastructure databases were retrieved. Data were extracted and pooled odds ratios with 95% confidence intervals were calculated. Seven studies...
Topics
- Asian People
- China
- Cytochrome P-450 CYP2E1
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Neoplasms
- Risk Factors
- Uterine Cervical Neoplasms