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Article

SPINK1 Promoter Variants Are Associated with Prostate Cancer Predisposing Alterations in Benign Prostatic Hyperplasia Patients.

Anticancer research - 1 Jul 2015

Winchester Danyelle, Ricks-Santi Luisel, Mason Tshela, Abbas Muneer, Copeland Robert L, Beyene Desta, Jingwi Emmanuel Y, Dunston Georgia M, Kanaan Yasmine M

Abstract excerpt

BACKGROUND/AIM: Several studies reported that patients with benign prostatic hyperplasia (BPH) experienced a 10% increased incidence of prostate cancer (PCa) after the first 5 years of diagnosis. We investigated the association between single nucleotide polymorphisms (SNPs) in the promoter of Serine Protease Inhibitor Kazal Type 1 (SPINK1) and the increased risk of BPH and PCa. MATERIALS AND METHODS: We genotyped...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Trypsin Inhibitor, Kazal Pancreatic

Source

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Identifiers

PMID: 26124326
PMCID: PMC4545211

Genes

SPINK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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